The Simpsons Meets The Pitt: 800th Episode Features Unexpected Crossover with Hit Medical Drama

The Simpsons, The Pitt

The Simpsons, The Pitt
  • Primary Subject: The Simpsons and The Pitt Crossover (Episode 800)
  • Key Update: The Simpsons celebrated its 800th episode milestone by featuring a high-intensity medical parody.
  • Status: Confirmed
  • Last Verified: February 16, 2026
  • Quick Answer: In its 800th episode, The Simpsons parodied The Pitt with cameos from Noah Wyle and the cast, blending medical melodrama with Santa’s Little Helper’s veterinary emergency.

The Simpsons recently aired its 800th episode, and it features an unexpected crossover with the hit medical drama series The Pitt. Here's how it all unfolded.

The historic episode of the iconic animated series saw Marge's crusade to get Santa's Little Helper in better shape result in a trip to the National Dog Show in Philadelphia, where Marge and Homer find themselves and their dog mixed up in a historical conspiracy adventure.

What Happened in The Simpsons and The Pitt Crossover?

The Simpsons 800th episode
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Credit: Fox

One of the key moments in the recent 800th episode of The Simpsons, titled "Irrational Treasure," is when Santa's Little Helper was sent to a veterinary hospital after eating several grapes out of Marge's ambrosia salad.

The family dog was attended by a familiar group of characters from The Pitt, with Noah Wyle, Katherine LaNasa, and Taylor Dearden themselves voicing the show's parody versions of their respective characters from the hit medical drama.

Considering that the series premiered just last year, fans were surprised to see it get a parody treatment from The Simpsons this early, and somehow they managed to get the real stars to voice their characters for the episode.

"Mike Price, the co-runner, co-producer of this episode, is a huge The Pitt fan, and we thought it'd be a fun way to spice up the veterinary scene by giving it the intensity and melodrama of this terrific show," showrunner Matt Selman explained to EW.

"And then we convinced Noah and some of the other actors to play intense vet cartoon versions of themself. But I think it came from Mike, because I know he was just the hugest fan of that show from the get-go and how crazy and intense it was."

Selman acknowledged that the show's parody of The Pitt in the recent episode was faster than the other pop culture references that they've made in the past.

"Usually we're like five years late or 13 years too late to something, but we're actually not super late to The Pitt, since season 2 is just coming out right now," he said. "Though I always think it's funny when people ding the show for being late to make fun of something, because at the very best, it was only on time once. And then every time after that, it was late."

What is the Future of The Simpsons?

The 800th episode of The Simpsons was also marked as the season 37 finale. However, fans have nothing to worry about since more seasons are currently in the works.

Last year, the series was renewed for four more seasons alongside the other Fox animated shows such as Family GuyBob's Burgers, and American Dad, extending its run until its 40th season.

There are no plans to end the series after its four-year renewal or any major changes to its cast and crew anytime soon.

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