With the return of Hazbin Hotel and the ongoing seasons of Invincible, Prime Video is on a roll in expanding its animation roster on the streaming platform.
Excluding anime, here are our top 10 must-watch animated series on Prime as of 2025, ranked from good to best!
Arthur (1996-2022)
Based on the books by Marc Brown, Arthur follows the eight-year-old aardvark of the same name with his family and friends as the animation focuses on exploring their childhood with school and valuing friendship. Despite being known as a children's show, Arthur has grown its own cult following for its viral memes.
Blue's Clues (1996-2025)
The Blue's Clues on Prime Video doesn't just include the modern, Blue's Clues & You, but even the original episodes featuring Steve Burns and Donovan Patton's Joe. If you're looking for a wholesome trip down memory lane, Blue's Clues might just be right up your alley.
Pink Panther Franchise
Silent animated slapstick comedy may be criminally overused in animation, but nothing beats Pink Panther when he does it. And if you're a fan, Prime Video streams its animation series and a couple of its movies.
The Boys Presents: Diabolical (2022)
If you're a fan of The Boys, then this animation spinoff's got everything you're looking for in an extra format. The Boys Presents: Diabolical is an anthology expanding the Boys Universe with its black humor, ultraviolence, and usual social satire about heroes. Turn The Boys into an animated series, and that's exactly what you get on Prime.
Teen Titans (2003-2006)
Follow a team of five teenage superheroes — Robin, Raven, Cyborg, Starfire, and Beast Boy — who live together and protect their city, Jump City, from villains while dealing with and navigating typical issues teenagers face among their peers.
The Second Best Hospital in the Galaxy (2024-Present)
Turn a cosmic workplace comedy into an animation and you've got The Second Best Hospital in the Galaxy, streaming on Prime Video since 2024. The series follows alien doctors Sleech (Keke Palmer) and Klak (Stephanie Hsu) as they find the cure to interdimensional illnesses and cosmic crises. And if there's anything animated shows on Prime know, it's witty satire comedies.
Batman: The Animated Series & Caped Crusader
Both Batman: The Animated Series and Caped Crusader are available to stream on Prime Video, so any DC fan looking to get to know more of the vigilante who fights crime in gothic Gotham City would best binge-watch their entirety on the streaming platform!
The Legend of Vox Machina (2022-Present)
If you're a fan of the Dungeons and Dragons campaign of Critical Role, The Legend of Vox Machina essentially adopts a group of seven misfit adventurers for hire. The animated series balances raunchy comedy, heartfelt camaraderie, and epic fantasy storytelling, making it one of Prime Video's most recommended must-watches!
Hazbin Hotel (2019-Present)
Hazbin Hotel began as an independent pilot that gained cult status and traction before landing on Prime Video. Set in Hell, Charlie Morningstar, the princess of Hell, wants to rehabilitate demons and reduce the overpopulation through her Hazbin Hotel plan. Oh, did I forget to mention it's also a musical with raunchy comedy, too?
Invincible (2021-Present)
While the superhero fatigue continues to persist, fans can be reassured that Invincible might just cleanse their palate on heroes, especially when this storytelling has a more adult approach.
It's not just the gore and the not-safe-for-work language, but the animation and the fourth-wall-breaking humor from time to time are exactly why adults should give Invincible a chance.
Out of everything on this list, which one's your top favorite animated show on Prime Video? Let us know in the comments.
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